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Immunotherapy Effects on Meningioma

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  • Anandhitha Arasu N/A

DOI:

https://doi.org/10.58445/rars.844

Keywords:

Immunotherapy, Meningioma, tumors

Abstract

Immunotherapy faces numerous challenges when treating brain and spinal tumors. The main challenge is eliminating the cancer cells without damaging the brain and spine. The review also focuses on how immunotherapy can only delay brain and spinal cancers but not fully treat them. This paper analyzes Pembrolizumab (Keytruda), a humanized monoclonal antibody which recent studies show as a promising option regarding meningioma and immunotherapy. Two clinical trials are further analyzed connecting immunotherapy and meningioma, with one still ongoing trial.

References

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Garzon-Muvdi, T., Bailey, D., Pernik, M., & Pan, E. (2020, August 28). Basis for immunotherapy for treatment of meningiomas. Frontiers in neurology. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7483661/#:~:text=PD%2DL1%20is%20expressed%20on,B%2Dcells%20(94).

Hospital, M. G. (2023). Immunotherapy delays disease progression of high-grade meningiomas. Massachusetts General Hospital. https://www.massgeneral.org/news/press-release/immunotherapy-delays-progression-of-meningiomas-2

Society, A. C. (2023). What is immunotherapy?: Immunotherapy for cancer. What Is Immunotherapy? | Immunotherapy for Cancer | American Cancer Society. https://www.cancer.org/cancer/managing-cancer/treatment-types/immunotherapy.html

Wirsching , H.-G., & Weller, M. (2023). Immunotherapy for meningiomas. Advances in experimental medicine and biology. https://pubmed.ncbi.nlm.nih.gov/37432631/

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Posted

2023-12-31

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