The Prospect of Vaccination of Haemophilus influenzae type b
DOI:
https://doi.org/10.58445/rars.817Keywords:
Haemophilus influenzae, vaccinationAbstract
Any type of infection that is caused by the gram-negative coccobacillus called Haemophilus influenzae is called a Haemophilus influenzae disease.1,2 Haemophilus influenzae type b (Hib), which is the most common Haemophilus influenzae disease, is a severe disease that is susceptible to anyone: but especially to infants and children as more than 10 million children younger than 5 years of age die annually.1,3 The main concern about this disease is that even though the vaccines have started to be widely used, there is not a well-developed vaccine that can detect and treat nontypeable strains for Hib.4,5 This should be very concerning to all as nontypeable H.influenzae (NTHi) causes invasive infections on children like pneumonia.4,6 This paper examines the current use of FDA approved Hib vaccines, predictions for vaccines that effectively treat nontypeable strains, and thoughts on protein and antigen candidates for the conjugate vaccines.
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