Preprint / Version 1

Blue light and health: A review of blue light and its structural and functional effects on children’s brains and neural development

##article.authors##

  • Pranauv Dev Muneeswaran High School Student at Polygence

DOI:

https://doi.org/10.58445/rars.543

Keywords:

blue light, neural development, circadian rhythm, melatonin suppression, learning disorders

Abstract

Light is essential to all life and is pivotal to humans' visual perception abilities. Without light, biological functioning would not be possible. Blue light, a higher-energy light with a shorter wavelength, makes up almost one-third of all visible light and is particularly known for its positive effects on cognitive function, mood regulation, and the body’s circadian rhythms. Recently, blue light has also been recognized as detrimental to the body’s health and there has been increased concern about the long-term effects of exposure to blue light during specific time periods in the day. These effects may include a loss of hormone secretion, retinal damage, disturbances in the body’s circadian rhythms, and more. Here, these impacts will be discussed in three distinct sections: circadian rhythms/melatonin secretion, retinal cells and visual perception, and other ramifications on human health. This paper will additionally address the advantages and disadvantages of blue light and specific physiological and psychological effects on the brain. This review will focus predominantly on children and their neural development. Structural and possible functional effects that blue light has on the brain will also be mentioned with a particular emphasis on children.  The objective of this paper is to recognize these effects and possibly find a correlation between such exposure and the development of specific health issues later in children’s lives. Using evidence from multiple studies and attributable data, this paper will provide an objective analysis that expands on current findings and provides insight into the lesser-known effects of blue light. Finally, possible recommendations and preventative measures that may arise due to these effects will also be discussed. 

References

Alkozei, A., Smith, R., Pisner, D. A., Vanuk, J. R., Berryhill, S. M., Fridman, A., ... & Killgore, W. D. (2016). Exposure to blue light increases subsequent functional activation of the prefrontal cortex during performance of a working memory task. Sleep, 39(9), 1671-1680. https://doi.org/10.5665/sleep.6090

Coats, J. G., Maktabi, B., Abou-Dahech, M. S., & Baki, G. (2021). Blue Light Protection, Part I-Effects of blue light on the skin. Journal of cosmetic dermatology, 20(3), 714–717. https://doi.org/10.1111/jocd.13837

Curcio, G., Ferrara, M., & De Gennaro, L. (2006). Sleep loss, learning capacity and academic performance. Sleep medicine reviews, 10(5), 323-337. https://doi.org/ 10.1016/j.smrv.2005.11.001

Davison, J. A., Patel, A. S., Cunha, J. P., Schwiegerling, J., & Muftuoglu, O. (2011). Recent studies provide an updated clinical perspective on blue light-filtering IOLs. Graefe's Archive for Clinical and Experimental Ophthalmology, 249, 957-968. https://doi.org/10.1007/s00417-011-1697-6

Esaki, Y., Kitajima, T., Ito, Y., Koike, S., Nakao, Y., Tsuchiya, A., ... & Iwata, N. (2016). Wearing blue light-blocking glasses in the evening advances circadian rhythms in the patients with delayed sleep phase disorder: An open-label trial. Chronobiology international, 33(8), 1037-1044. https://doi.org/ 10.1080/07420528.2016.1194289

Hosseinzadeh Javary, F. Z., Jenaabadi, H., & Farnam, A. (2020). The Effect of Modifying the Sleep Pattern on Reducing the Math Learning Disorder among Elementary School Students. International Journal of Pediatrics, 8(10), 12197-12204. https://doi.org/10.22038/ijp.2020.51757.4116

Kocevska, D., Muetzel, R. L., Luik, A. I., Luijk, M. P., Jaddoe, V. W., Verhulst, F. C., ... & Tiemeier, H. (2017). The developmental course of sleep disturbances across childhood relates to brain morphology at age 7: the Generation R Study. Sleep, 40(1), zsw022. https://doi.org/10.1093/sleep/zsw022

Leid, J. (2016). Blue light: What are the risks to our eyes?. Points de Vue: International Review Ophthalmic Optics, 1-7. https://doi.org/10.1007/s40123-023-00675-3

Niwano, Y., Kanno, T., Iwasawa, A., Ayaki, M., & Tsubota, K. (2014). Blue light injures corneal epithelial cells in the mitotic phase in vitro. The British journal of ophthalmology, 98(7), 990–992. https://doi.org/10.1136/bjophthalmol-2014-305205. https://doi.org/ 10.1136/bjophthalmol-2014-305205

Ouyang, X. I. N. L. I., Yang, J., Hong, Z., Wu, Y., Xie, Y., & Wang, G. (2020). Mechanisms of blue light-induced eye hazard and protective measures: A review. Biomedicine & Pharmacotherapy, 130, 110577. https://doi.org/ 10.1016/j.biopha.2020.110577

Short, M. A., Bartel, K., & Carskadon, M. A. (2019). Sleep and mental health in children and adolescents. In Sleep and health (pp. 435-445). Academic Press. https://doi.org/10.1016/B978-0-12-815373-4.00032-0

Stern, M., Broja, M., Sansone, R., Gröne, M., Skene, S. S., Liebmann, J., ... & Heiss, C. (2018). Blue light exposure decreases systolic blood pressure, arterial stiffness, and improves endothelial function in humans. European journal of preventive cardiology, 25(17), 1875-1883. https://doi.org/10.1177/2047487318800072

Wahl, S., Engelhardt, M., Schaupp, P., Lappe, C., & Ivanov, I. V. (2019). The inner clock—Blue light sets the human rhythm. Journal of biophotonics, 12(12), e201900102. https://doi.org/10.1002/jbio.201900102

Zhao, Z. C., Zhou, Y., Tan, G., & Li, J. (2018). Research progress about the effect and prevention of blue light on eyes. International journal of ophthalmology, 11(12), 1999. https://doi.org/ 10.18240/ijo.2018.12.20

Downloads

Posted

2023-10-08