Exploring relationship between ACL injuries and reaction time, hormonal changes, and environmental factors
DOI:
https://doi.org/10.58445/rars.3436Keywords:
ACL, AnatomyAbstract
In the United States, around 100,000 to 250,000 people experience ACL injuries annually,
calling for major surgery and 9-12 months of recovery time. This results in less physical activity
and difficulty in activities of daily living. In this review paper, we will discuss the relationship
between ACL injuries and reaction time, hormonal changes, and environmental factors. This, as
a result, will help us determine the severity of the impact of each factor on ACL tears.
Furthermore, it provides us with a greater understanding of how performance is altered
post-injury. Additionally, it is important to gain a greater knowledge of how baseline neural
cognition and reaction time may relate to the risk of experiencing an ACL injury. It is important to
understand the differences in injury risk between males and females, specifically the anatomy
and growth rate paired with hormonal changes that could occur. Ultimately, this will develop our
understanding of the after-effects of ACL injuries, such as post-traumatic osteoarthritis, and how
future prevention programs may be altered to adapt to such scenarios.
References
References
Boden, B. P., Sheehan, F. T., & Torg, J. S. (2013). Non-contact ACL Injuries: Mechanisms and Risk Factors.
Cimino, F., & Volk, B. S. (2010). Anterior Cruciate Ligament Injury: Diagnosis, Management, and Prevention. American Family Physician, 82(8), 917–922.
Clar, C., Fischerauer, S. F., Leithner, A., Rasic, L., Ruckenstuhl, P., & Sadoghi, P. (2025). Reducing ACL injury risk: A meta‐analysis of prevention programme effectiveness. Knee Surgery, Sports Traumatology, Arthroscopy, 33(8), 2815–2824. https://doi.org/10.1002/ksa.12542
Devana, S. K., Solorzano, C., Nwachukwu, B., & Jones, K. J. (2022). Disparities in ACL Reconstruction: The Influence of Gender and Race on Incidence, Treatment, and Outcomes. Current Reviews in Musculoskeletal Medicine, 15(1), 1–9. https://doi.org/10.1007/s12178-021-09736-1
Grooms, D. R., Bizzini, M., Silvers-Granelli, H., & Benjaminse, A. (2024). Neurocognitive & Ecological Motor Learning Considerations for the 11+ ACL Injury Prevention Program: A Commentary. International Journal of Sports Physical Therapy, 19(11). https://doi.org/10.26603/001c.123956
Larwa, J., Stoy, C., Chafetz, R. S., Boniello, M., & Franklin, C. (2021). Stiff Landings, Core Stability, and Dynamic Knee Valgus: A Systematic Review on Documented Anterior Cruciate Ligament Ruptures in Male and Female Athletes. International Journal of Environmental Research and Public Health, 18(7), 3826. https://doi.org/10.3390/ijerph18073826
Lu, B. H., Harper, S. A., Bolton, D. A. E., & Beethe, A. Z. (n.d.). Reaction Times Altered by Anterior Cruciate Ligament Tear.
Markatos, K., Kaseta, M. K., Lallos, S. N., Korres, D. S., & Efstathopoulos, N. (2013). The anatomy of the ACL and its importance in ACL reconstruction. European Journal of Orthopaedic Surgery & Traumatology, 23(7), 747–752. https://doi.org/10.1007/s00590-012-1079-8
Orchard, J., Seward, H., McGivern, J., & Hood, S. (2001). Intrinsic and Extrinsic Risk Factors for Anterior Cruciate Ligament Injury in Australian Footballers. The American Journal of Sports Medicine, 29(2), 196–200. https://doi.org/10.1177/03635465010290021301
Paterno, M. V. (2015). Incidence and Predictors of Second Anterior Cruciate Ligament Injury After Primary Reconstruction and Return to Sport. Journal of Athletic Training, 50(10), 1097–1099. https://doi.org/10.4085/1062-6050-50.10.07
Petushek, E. J., Sugimoto, D., Stoolmiller, M., Smith, G., & Myer, G. D. (2019). Evidence-Based Best-Practice Guidelines for Preventing Anterior Cruciate Ligament Injuries in Young Female Athletes: A Systematic Review and Meta-analysis. The American Journal of Sports Medicine, 47(7), 1744–1753. https://doi.org/10.1177/0363546518782460
Posch, M., Ruedl, G., Greier, K., Faulhaber, M., Tecklenburg, K., Schranz, A., Schliernzauer, B., & Burtscher, M. (2023). Impact of Environmental Factors on the ACL Injury Risk in Recreational Alpine Skiing. International Journal of Sports Medicine, 44(13), 1003–1008. https://doi.org/10.1055/a-2134-3908
Reiche, E., Collins, K., Genoese, F., Walaszek, M., Triplett, A., Kuenze, C., Harkey, M., & Baez, S. (2024). Lower Extremity Reaction Time in Individuals With Contact Versus Noncontact Anterior Cruciate Ligament Injuries After Reconstruction. Journal of Athletic Training, 59(1), 66–72. https://doi.org/10.4085/1062-6050-0428.22
Shimokochi, Y., & Shultz, S. J. (2008). Mechanisms of Noncontact Anterior Cruciate Ligament Injury. Journal of Athletic Training, 43(4), 396–408. https://doi.org/10.4085/1062-6050-43.4.396
Slauterbeck, J. R., Fuzie, S. F., Smith, M. P., Clark, R. J., Xu, K. T., Starch, D. W., & Hardy, D. M. (n.d.). The Menstrual Cycle, Sex Hormones, and Anterior Cruciate Ligament Injury.
The female ACL: Why is it more prone to injury? (2016). Journal of Orthopaedics, 13(2), A1–A4. https://doi.org/10.1016/S0972-978X(16)00023-4
Xiao, M., Lemos, J. L., Hwang, C. E., Sherman, S. L., Safran, M. R., & Abrams, G. D. (2022). Increased Risk of ACL Injury for Female but Not Male Soccer Players on Artificial Turf Versus Natural Grass: A Systematic Review and Meta-Analysis. Orthopaedic Journal of Sports Medicine, 10(8), 23259671221114353. https://doi.org/10.1177/23259671221114353
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