Preprint / Version 1

Valvular Heart Diseases: Insights and Perspectives

##article.authors##

  • Jiayin Li Santa Margarita Catholic High School

DOI:

https://doi.org/10.58445/rars.2543

Keywords:

Treatments, Technology, Heart, Cardiology, Diseases

Abstract

Heart valves maintain the unidirectional blood flow ensuring effective cardiac functioning. Currently, over 74 million people worldwide suffer from valvular heart ailments such as regurgitation and stenosis. This review focuses on the structures and mechanisms of the four major valves, aortic, mitral, tricuspid, and pulmonary valves  comprehending the biology and clinical aspects of both congenital and acquired valvular diseases. This manuscript reviews emerging updates in transcatheter mitral valve repair, transcatheter aortic valve replacement, and stem cells based approaches for the management of various valvular diseases. Additionally, the article provides insights into computational models and artificial intelligence in next generation valvular therapies.

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2025-05-10

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