What is the burden of bacterial infections causing neonatal sepsis in people between the ages of infants under 90 days old living in Eastern-Sub-Saharan Africa and the changes in the sea levels of the Indian Ocean from 2000-2018?
DOI:
https://doi.org/10.58445/rars.2198Keywords:
Neonatal sepsis, Eastern sub-Saharan Africa, Burden of Neonatal Sepsis, Climate Change, Indian Ocean Sea LevelsAbstract
This research is a literature review regarding the burden of bacteria infections causing neonatal sepsis in people between the ages of newborn to 90 days-old living in Eastern-Sub-Saharan Africa and the changes in the sea levels of the Indian Ocean. Through a literature review, correlation between the two will be found and explained. External factors that may be influencing the burden of neonatal sepsis in people between the ages of newborn to 90 days-old living in Eastern-Sub-Saharan African will also be considered to ensure that the correlation between the burden of neonatal sepsis in the labeled demographic and rising sea levels in the Indian Ocean is real. Further steps to decrease the rates of neonatal sepsis in people between the ages of newborn to 90 days-old living in Eastern-Sub-Saharan African will also be explained. These methods will be related to the decrease of climate change and specific to the region being discussed. Figures and models are included to better explain the correlation and the best way to prevent the incidence rates of neonatal sepsis from increasing.
References
Asadgol, Z., Mohammadi, H., Kermani, M., Badirzadeh, A., & Gholami, M. (2019). The effect of climate change on cholera disease: The road ahead using artificial neural network. PLOS ONE, 14(11). https://doi.org/10.1371/journal.pone.0224813
Attia Hussein Mahmoud, H., Parekh, R., Dhandibhotla, S., Sai, T., Pradhan, A., Alugula, S., Cevallos-Cueva, M., Hayes, B. K., Athanti, S., Abdin, Z., & K, B. (2023). Insight into neonatal sepsis: An overview. Cureus. https://doi.org/10.7759/cureus.45530
Binder, L., Gleixner, S., Gornott, C., Lange, S., Šedová, B., & Tomalka, J. (2023, March). Climate risk profile for eastern africa. https://weatheringrisk.org/sites/default/files/document/Climate-Risk-Profile_Eastern-Africa.pdf
Centers for Disease Control and Prevention. (2024, March 8). About sepsis. Centers for Disease Control and Prevention. https://www.cdc.gov/sepsis/about/index.html
Climate risk profile for eastern africa. PIK. (2023). https://weatheringrisk.org/sites/default/files/document/Climate-Risk-Profile_Eastern-Africa.pdf
Cruz-Urbano, J. (2024, September 5). Neonatal sepsis: Understanding and preventing risks for your newborn " Sepsis and critical illness research center " college of medicine " university of florida. UF Health. https://scirc.med.ufl.edu/2024/09/06/neonatal-sepsis-understanding-and-preventing-risks-for-your-newborn/#:~:text=Neonatal%20sepsis%20is%20distinct%20from,days%2C%20often%20affecting%20premature%20infants.
Deaton, A. S., & Tortora, R. (2015a). People in sub-saharan africa rate their health and health care among the lowest in the world. Health Affairs, 34(3), 519–527. https://doi.org/10.1377/hlthaff.2014.0798
Delaporte, A. (2023, November 30). New insights on mobile internet connectivity in Sub-Saharan africa. Mobile for Development. https://www.gsma.com/solutions-and-impact/connectivity-for-good/mobile-for-development/blog/new-insights-on-mobile-internet-connectivity-in-sub-saharan-africa/
How global warming threatens human security in Africa – Africa Center. Africa Center for Strategic Studies. (2021, October 29). https://africacenter.org/spotlight/how-global-warming-threatens-human-security-in-africa/
Huang, L., Zhuang, W., Lu, W., Zhang, Y., Edwing, D., & Yan, X. (2023). Rapid sea level rise in the Tropical Southwest Indian Ocean in the recent two decades. Geophysical Research Letters, 51(1). https://doi.org/10.1029/2023gl106011
Kiya, G. T., Mekonnen, Z., Melaku, T., Tegene, E., Gudina, E. K., Cools, P., & Abebe, G. (2024). Prevalence and mortality rate of sepsis among adults admitted to hospitals in sub-Saharan Africa: a systematic review and meta-analysis. The Journal of hospital infection, 144, 1–13. https://doi.org/10.1016/j.jhin.2023.11.012
Li, J., Shen, L., & Qian, K. (2023). Global, regional, and national incidence and mortality of neonatal sepsis and other neonatal infections, 1990–2019. Frontiers in Public Health, 11. https://doi.org/10.3389/fpubh.2023.1139832
Lu, Y., Li, Y., Duan, J., Lin, P., & Wang, F. (2022). Multidecadal sea level rise in the Southeast Indian Ocean: The role of Ocean Salinity Change. Journal of Climate, 35(5), 1479–1496. https://doi.org/10.1175/jcli-d-21-0288.1
Lynch, V. D., & Shaman, J. (2023). Waterborne Infectious Diseases Associated with Exposure to Tropical Cyclonic Storms, United States, 1996-2018. Emerging infectious diseases, 29(8), 1548–1558. https://doi.org/10.3201/eid2908.221906
Magnano San Lio, R., Favara, G., Maugeri, A., Barchitta, M., & Agodi, A. (2023a). How antimicrobial resistance is linked to climate change: An overview of two intertwined global challenges. International Journal of Environmental Research and Public Health, 20(3), 1681. https://doi.org/10.3390/ijerph20031681
Minasyan, H. (2019). Sepsis: Mechanisms of bacterial injury to the patient. Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, 27(1). https://doi.org/10.1186/s13049-019-0596-4
Monegro, A. F., Muppidi, V., & Regunath, H. (2023). Hospital-Acquired Infections. National Library of Medicine.
NASA. (2023, August 14). NASA study reveals compounding climate risks at two degrees of warming – climate change: Vital signs of the planet. NASA. https://climate.nasa.gov/news/3278/nasa-study-reveals-compounding-climate-risks-at-two-degrees-of-warming/
Polat, G., Ugan, R. A., Cadirci, E., & Halici, Z. (2017). Sepsis and septic shock: Current treatment strategies and new approaches. The Eurasian Journal of Medicine, 49(1), 53–58. https://doi.org/10.5152/eurasianjmed.2017.17062
Ranjeva, S. L., Warf, B. C., & Schiff, S. J. (2018). Economic burden of neonatal sepsis in sub-saharan africa. BMJ Global Health, 3(1). https://doi.org/10.1136/bmjgh-2017-000347
Sepsis: Symptoms, causes, treatment & prevention. Cleveland Clinic. (2024, May 1). https://my.clevelandclinic.org/health/diseases/12361-sepsis
Septicemia. Johns Hopkins Medicine. (2024, April 29). https://www.hopkinsmedicine.org/health/conditions-and-diseases/septicemia#:~:text=Sepsis%20is%20your%20body’s%20most,up%20to%20half%20of%20cases.
Slomski, K. (2023, May 1). Health care in sub-saharan africa: 21st Century trends & forecasts. D’Amore-McKim School of Business. https://damore-mckim.northeastern.edu/news/health-care-in-sub-saharan-africa-21st-century/
Somalia (SOM) and Uganda (UGA) trade. The Observatory of Economic Complexity. (n.d.-a). https://oec.world/en/profile/bilateral-country/som/partner/uga
Srzić, I. (2022). Sepsis definition: What’s new in the Treatment Guidelines. Acta Clinica Croatica. https://doi.org/10.20471/acc.2022.61.s1.11
Sub-Saharan Africa poverty rate 1990-2024. MacroTrends. (n.d.-b). https://www.macrotrends.net/global-metrics/countries/SSF/sub-saharan-africa-/poverty-rate#:~:text=Sub%2DSaharan%20Africa%20poverty%20rate%20for%202019%20was%2087.30%25%2C,a%200%25%20increase%20from%202015
Treatment. Sepsis Alliance. (2021, March 25). https://www.sepsis.org/sepsis-basics/treatment/
World Health Organization. (2023, September 18). Billions left behind on the path to Universal Health Coverage. World Health Organization. https://www.who.int/news/item/18-09-2023-billions-left-behind-on-the-path-to-universal-health-coverage#:~:text=In%202021%2C%20about%204.5%20billion,covered%20by%20essential%20health%20services
World Health Organization. (2024a, April 30). Cholera upsurge. World Health Organization. https://www.who.int/emergencies/situations/cholera-upsurge
World Health Organization. (2024b, May 3). Sepsis. World Health Organization. https://www.who.int/news-room/fact-sheets/detail/sepsis#:~:text=Key%20facts,all%20global%20deaths%20(2)
World Health Organization. (2024c, September 4). Cholera. World Health Organization. https://www.who.int/news-room/fact-sheets/detail/cholera
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