Preprint / Version 1

Genetic Vulnerability: PIK3CA Gene Dependency in HER2-Positive Breast Ductal Carcinoma

##article.authors##

  • Pranav Potluri Denmark High School
  • Jude Raj Duke University

DOI:

https://doi.org/10.58445/rars.204

Keywords:

Breast Ductal Carcinoma, Genetics

Abstract

In the medical world, a multitude of revolutionary technologies have been developed to improve the process of diagnosing and treating a patient. In the modern era, one of the most innovative developments is the use of CRISPR-Cas9, an enzyme that uses palindromic sequences of nucleotides to bind to and delete or edit DNA. Although heavily studied as a genetic engineering tool, this fascinating protein can also identify genetic targets to improve cancer therapy through CRISPR screening.

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Posted

2023-06-22