Cannabis Use in Adolescents
Effects and Treatment Approaches
DOI:
https://doi.org/10.58445/rars.1730Keywords:
neurology, adolescence, biologyAbstract
This research paper intends to focus on the neurological effects of recreational cannabis use, particularly in adolescence. The use of cannabis recreationally in the United States has increased immensely over the last decade. However, more information is needed to further analyze the effects on the developing brain over time. This paper will cover the effects on neuro-physical responses as a result of chronic cannabis use such as neurological, emotional, physical, and cognitive effects. The correlation between cannabis and neurological and mood disorders will also be discussed. The underlying effects of chronic use of cannabis will also be explored through a discussion of treatments and possible therapies to reverse the damaging results of the drug. The purpose of this paper is to shine a light on this topic in hopes of informing those of the consequences of using cannabis during adolescence.
References
Archie, S. R., & Cucullo, L. (2019). Harmful Effects of Smoking Cannabis: A Cerebrovascular
and Neurological Perspective. Frontiers in pharmacology, 10, 1481.
https://doi.org/10.3389/fphar.2019.01481
Ashton, C. H. (2001). Pharmacology and effects of cannabis: a brief review. Br. J. Psychiatry
, 101–106. doi: 10.1192/bjp.178.2.101 (link:
Atakan, Z. (2012). Cannabis, a complex plant: different compounds and different effects on
individuals. Therapeutic advances in psychopharmacology, 2(6), 241-254.
Hall W, Degenhardt L (2009) Adverse health effects of non-medical cannabis use. Lancet
: 1383–1391. (link: https://www.sciencedirect.com/science/article/abs/pii/S0140673609610370)
Hirvonen, J., Goodwin, R. S., Li, C. T., Terry, G. E., Zoghbi, S. S., Morse, C., Pike, V. W.,
Volkow, N. D., Huestis, M. A., & Innis, R. B. (2012). Reversible and regionally selective
downregulation of brain cannabinoid CB1 receptors in chronic daily cannabis smokers.
Molecular psychiatry, 17(6), 642–649. https://doi.org/10.1038/mp.2011.82
NIDA. 2023, January 23. What is the scope of cannabis (marijuana) use in the United States?.
Retrieved from https://nida.nih.gov/publications/research-reports/marijuana/what-scope-marijuana-use-in-united-states
NIDA. 2021, April 19. What are marijuana's effects?. Retrieved from
https://nida.nih.gov/publications/research-reports/marijuana/what-are-marijuana-effects
Zehra, A., Burns, J., Liu, C. K., Manza, P., Wiers, C. E., Volkow, N. D., & Wang, G. J. (2018).
Cannabis Addiction and the Brain: a Review. Journal of neuroimmune pharmacology :
the official journal of the Society on NeuroImmune Pharmacology, 13(4), 438–452.
https://doi.org/10.1007/s11481-018-9782-9
Cousijn, J., Wiers, R. W., Ridderinkhof, K. R., van den Brink, W., Veltman, D. J., & Goudriaan,
A. E. (2012). Grey matter alterations associated with cannabis use: results of a VBM
study in heavy cannabis users and healthy controls. Neuroimage, 59(4), 3845-3851.
doi:10.1016/j.neuroimage.2011.09.046
Crean, R. D., Crane, N. A., & Mason, B. J. (2011). An evidence based review of acute and
long-term effects of cannabis use on executive cognitive functions. Journal of addiction
medicine, 5(1), 1–8. https://doi.org/10.1097/ADM.0b013e31820c23fa
Mancall, E.L., Brock, D.G. (2011). Gray’s Clinical Neuroanatomy: The Anatomic Basis for
Clinical Neuroscience. Elsevier.
Filley, C.M, Douglas, R.D. (2016). White matter and cognition: making the connection. Journal
of Neurophysiology, 116: 2093–2104. doi:10.1152/jn.00221.2016.
Jonsson, A. J., Birgisdottir, H., & Sigurdsson, E. (2014). Eykur notkun kannabis hættu á geðrofi
og þróun geðklofa? [Does the use of cannabis increase the risk for psychosis and the
development of schizophrenia?]. Laeknabladid, 100(9), 443–451.
https://doi.org/10.17992/lbl.2014.09.556
Moussouttas, Michael MD. Cannabis Use and Cerebrovascular Disease. The Neurologist 10(1):p 47-53, January 2004. | DOI: 10.1097/01.nrl.0000107493.19282.b0
Thomas, G., Kloner, R. A., & Rezkalla, S. (2014). Adverse cardiovascular, cerebrovascular, and peripheral vascular effects of marijuana inhalation: what cardiologists need to know. The American journal of cardiology, 113(1), 187-190.
Sekhon S, Gupta V. Mood Disorder. [Updated 2023 May 8]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK558911/
Sherman, B. J., & McRae-Clark, A. L. (2016). Treatment of Cannabis Use Disorder: Current Science and Future Outlook. Pharmacotherapy, 36(5), 511–535. https://doi.org/10.1002/phar.1747
Sorensen, C. J., DeSanto, K., Borgelt, L., Phillips, K. T., & Monte, A. A. (2017). Cannabinoid Hyperemesis Syndrome: Diagnosis, Pathophysiology, and Treatment-a Systematic Review. Journal of medical toxicology : official journal of the American College of Medical Toxicology, 13(1), 71–87. https://doi.org/10.1007/s13181-016-0595-z
Thanvi, B. R., and Treadwell, S. D. (2009). Cannabis and stroke: is there a link? Postgrad Med. J. 85, 80–83. doi: 10.1136/pgmj.2008.070425
Zhuo, C., Tian, H., Song, X., Jiang, D., Chen, G., Cai, Z., Ping, J., Cheng, L., Zhou, C., & Chen,
C. (2023). Microglia and cognitive impairment in schizophrenia: translating scientific progress into novel therapeutic interventions. Schizophrenia (Heidelberg, Germany), 9(1), 42. https://doi.org/10.1038/s41537-023-00370-z
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