Preprint / Version 1

Analysis of machine learning and deep learning models for early Alzheimer's disease diagnosis

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  • Vanshika Rathi Student

DOI:

https://doi.org/10.58445/rars.1722

Keywords:

Alzheimer's Disease, Machine learning, Deep learning, Models, Early diagnosis

Abstract

Machine learning (ML) models and deep learning (DL) algorithms have become widely utilized tools in the healthcare sector. They are helpful in identifying patterns, analyzing imaging data, and utilizing various biomarkers to identify between a healthy and unhealthy individual. This technology contributes to confirming early diagnoses, particularly for Alzheimer’s disease, and mild cognitive impairments (MCIs). Alzheimer’s disease is a neurological disorder that causes memory loss and inhibits the individual’s ability to function independently. This paper compares the ML models used to classify the disease, differentiating between how often they are used and their accuracy. The ML models include support vector machines (SVMs), random forest (RF), and logistic regression, while the DL algorithms utilized include convolutional neural networks (CNNs) and recurrent neural networks (RNNs). Through the comparison, we find that the most effective ML models are SVMs due to their ability to handle large datasets and provide precise image classification, whereas the most effective DL models are CNNs, because of their multiple variations in structures and highest accuracy rates in analyzing patterns in medical images through in-depth analysis for early AD diagnosis.

References

V. Rajak, A. Rajak, A. K. Shrivastava. Diagnosis of Alzheimer disease using machine learning approaches. International Journal of Advanced Science and Technology, (2019). https://www.researchgate.net/profile/Akash-Rajak/publication/342847161_Diagnosis_of_Alzheimer_Disease_using_Machine_Learning_Approaches/links/5f0b37c6a6fdcc4ca463942e/Diagnosis-of-Alzheimer-Disease-using-Machine-Learning-Approaches.pdf

M. M. Ahsan, S. A. Luna, Z. Siddique. Machine-learning-based disease diagnosis: A comprehensive review. MDPI, (2022). https://www.mdpi.com/2227-9032/10/3/541

M. G. Alsubaie, S. Luo, K. Shaukat. Alzheimer’s disease detection using deep learning on neuroimaging: A systematic review. MDPI, (2024). https://www.mdpi.com/2504-4990/6/1/24#:~:text=Deep%20learning%20models%20have%20emerged,from%20 large%2d Scale%20 imaging%20 datasets

A. D. Arya, S. S. Verma, P. Chakarabarti, T. Chakrabarti, A. A. Elngar, A.-M. Kamali, M. Nami. A systematic review on machine learning and deep learning techniques in the effective diagnosis of Alzheimer’s disease. Brain Informatics, (2023). https://link.springer.com/article/10.1186/s40708-023-00195-7#Bib1

S. Sharma, A. Sharma. A deep learning based convolutional neural network model with VGG16 feature extractor for the detection of Alzheimer disease using MRI scans. Measurement: Sensors, (2022). https://www.sciencedirect.com/science/article/pii/S2665917422001404

G. Battineni, G. G. Sagaro, N. Chinatalapudi, F. Amenta. Applications of machine learning predictive models in the chronic disease diagnosis. MDPI, (2020). https://www.mdpi.com/2075-4426/10/2/21

M. B. T. Noor, N. Z. Zenia, M. S. Kaiser, S. A. Mamun, M. Mahmud. Application of deep learning in detecting neurological disorders from magnetic resonance images: survey on the detection of Alzheimer’s disease, Parkinson’s disease and schizophrenia. Brain Informatics, (2020). https://braininformatics.springeropen.com/articles/10.1186/s40708-020-00112-2#Sec29

A. Rahman, T. Debnath, D. Kundu, M. S. I. Khan, A. A. Aishi, S. Sazzad, M. Sayduzzaman, S. S. Band. Machine learning and deep learning-based approach in smart healthcare: Recent advances, applications, challenges and opportunities. AIMS Public Health, (2024). https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11007421/

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Posted

2024-10-03