Preprint / Version 1

Impact of the COVID-19 Pandemic on Lung Cancer Patients

##article.authors##

  • Zhen Tao Polygence

DOI:

https://doi.org/10.58445/rars.121

Keywords:

COVID-19, Lung Cancer, Patients

Abstract

SARS-CoV-2 is a highly infectious respiratory virus that has caused a global pandemic called coronavirus disease 2019 or COVID-19. This virus forced many countries to lock down and has resulted in a very high death toll. Notably, COVID-19 has greatly impacted people with lung cancer. Lung cancer, most often affecting people 65 years of age or older, is the third most common cancer diagnosis in the United States and has the highest cancer-related mortality rate. As COVID-19 has infected more people and developed new variants, many lung cancer patients have faced decreased accessibility to physician consultation, reduced availability of lung cancer screening appointments, and postponement of their treatment plans. Because doctors and nurses have been overrun with treating and monitoring those with COVID-19, lung cancer patients have found fewer physicians available for either consultation or testing. The shortage of doctors and technicians has decreased the number of appointment times available for lung cancer screening, which is critical in the early detection of lung cancer. Furthermore, forced postponement of treatment plans for those with lung cancer has been evident for both COVID-infected and non-COVID-infected lung cancer patients due to a lack of knowledge about the consequences of mixed treatments and a shortage of doctors and supplies. These factors have resulted in detrimental health consequences for lung cancer patients around the world. 

References

Addeo, Alfredo, et al. “COVID-19 and Lung Cancer: Risks, Mechanisms and Treatment Interactions.” Journal for ImmunoTherapy of Cancer, vol. 8, no. 1, May 2020, p. e000892, www.ncbi.nlm.nih.gov/pmc/articles/PMC7246105/, 10.1136/jitc-2020-000892.

American Cancer Society. “Lung Cancer Statistics | How Common Is Lung Cancer?” Cancer.org, 2022, www.cancer.org/cancer/lung-cancer/about/key-statistics.html.

Aiyegbusi, Olalekan Lee, et al. “Symptoms, Complications and Management of Long COVID: A Review.” Journal of the Royal Society of Medicine, vol. 114, no. 9, 15 July 2021, pp. 428–442, journals.sagepub.com/doi/full/10.1177/01410768211032850, 10.1177/01410768211032850.

Cafarotti, Stefano, and Miriam Patella. “Lung Cancer Surgical Management during the Outbreak of Coronavirus Disease 2019.” Journal of Thoracic Oncology, vol. 15, no. 6, June 2020, p. e81, www.jto.org/article/S1556-0864(20)30291-4/fulltext, 10.1016/j.jtho.2020.03.027.

Cascella, Marco, et al. “Features, Evaluation, and Treatment of Coronavirus (COVID-19).” Nih.gov, StatPearls Publishing, 4 May 2022, www.ncbi.nlm.nih.gov/books/NBK554776/.

Cooley, Mary E. “Symptoms in Adults with Lung Cancer.” Journal of Pain and Symptom Management, vol. 19, no. 2, Feb. 2000, pp. 137–153, www.sciencedirect.com/science/article/pii/S0885392499001505, 10.1016/s0885-3924(99)00150-5.

Dingemans, Anne-Marie C., et al. “Treatment Guidance for Patients with Lung Cancer during the Coronavirus 2019 Pandemic.” Journal of Thoracic Oncology, vol. 15, no. 7, July 2020, pp. 1119–1136, www.sciencedirect.com/science/article/pii/S1556086420303828, 10.1016/j.jtho.2020.05.001.

Elkrief, Arielle, et al. “Changes in Lung Cancer Treatment as a Result of the Coronavirus Disease 2019 Pandemic.” JAMA Oncology, vol. 6, no. 11, 1 Nov. 2020, p. 1805, jamanetwork.com/journals/jamaoncology/article-abstract/2770258, 10.1001/jamaoncol.2020.4408.

Fedewa, Stacey. “Lung Cancer Screening Rates Improved in 19 States despite the COVID-19 Pandemic - the ASCO Post.” Ascopost.com, 2022, ascopost.com/news/august-2021/lung-cancer-screening-rates-improved-in-19-states-despite-the-covid-19-pandemic/#:~:text=The%20report%20showed%20that%20nationally,in%202019%20and%202020%2C%20respectively.

Fujita, Kohei, et al. “Impact of COVID ‐19 Pandemic on Lung Cancer Treatment Scheduling.” Thoracic Cancer, vol. 11, no. 10, 12 Aug. 2020, pp. 2983–2986, onlinelibrary.wiley.com/doi/full/10.1111/1759-7714.13615, 10.1111/1759-7714.13615.

He, Feng, et al. “Coronavirus Disease 2019: What We Know?” Journal of Medical Virology, vol. 92, no. 7, 28 Mar. 2020, pp. 719–725, onlinelibrary.wiley.com/doi/full/10.1002/jmv.25766, 10.1002/jmv.25766.

Johns Hopkins Medicine. “Lung Cancer Screening.” Hopkinsmedicine.org, 8 Aug. 2021, www.hopkinsmedicine.org/health/conditions-and-diseases/lung-cancer/lung-cancer-screening#:~:text=The%20most%20common%20types%20of,rays%20and%20sputum%20cytology%20tests.

Kannampallil, Thomas G., et al. “Exposure to COVID-19 Patients Increases Physician

Trainee Stress and Burnout.” PLOS ONE, vol. 15, no. 8, 6 Aug. 2020, p. E0237301, www.ncbi.nlm.nih.gov/pmc/articles/PMC7410237/, 10.1371/journal.pone.0237301.

“Number of COVID-19 Patients in Hospital.” Our World in Data, ourworldindata.org/grapher/current-covid-patients-hospital. Accessed 23 June 2022.

Lamiani, Giulia, et al. “Hospital Employees’ Well-Being Six Months after the COVID-19 Outbreak: Results from a Psychological Screening Program in Italy.” International Journal of Environmental Research and Public Health, vol. 18, no. 11, 25 May 2021, p. 5649, www.mdpi.com/1660-4601/18/11/5649, 10.3390/ijerph18115649.

LaPointe, Jacqueline. ““Great Resignation” Hits Healthcare Hard as Physician Burnout Persists.” RevCycleIntelligence, 26 Oct. 2021, revcycleintelligence.com/news/great-resignation-hits-healthcare-hard-as-physician-burnout-persists.

Liu, Ran, et al. “The Physician Scheduling of Fever Clinic in the COVID-19 Pandemic.” IEEE Transactions on Automation Science and Engineering, vol. 19, no. 2, Apr. 2022, pp. 709–723, ieeexplore.ieee.org/abstract/document/9555372, 10.1109/tase.2021.3114339.

Mazzone, Peter J, et al. “Management of Lung Nodules and Lung Cancer Screening During the COVID-19 Pandemic.” Thoracic Oncology Guidelines and Consensus Statements, vol. 158, no. 1, July. 2020, pp. 406-415, https://dpl6hyzg28thp.cloudfront.net/media/Mazzone.pdf.

Minna, John D, et al. “Focus on Lung Cancer.” Cancer Cell, vol. 1, no. 1, Feb. 2002, pp. 49–52, www.cell.com/fulltext/S1535-6108(02)00027-2, 10.1016/s1535-6108(02)00027-2.

Moris D;Felekouras E. “Surgery Scheduling in a Crisis: Effect on Cancer Patients.” Journal of B.U.ON. : Official Journal of the Balkan Union of Oncology, vol. 25, no. 4, 2020, pubmed.ncbi.nlm.nih.gov/33099963/.

Murphy, Kathleen. “SARS CoV-2 Detection from Upper and Lower Respiratory Tract Specimens.” Chest, vol. 158, no. 5, Nov. 2020, pp. 1804–1805, www.ncbi.nlm.nih.gov/pmc/articles/PMC7610136/, 10.1016/j.chest.2020.07.061.

Palmore, Tara N., Smith, Becky A. “COVID-19: General approach to infection prevention nt he heatlh care setting” Uptodate.com, May 2022, www.uptodate.com/contents/covid-19-general-approach-to-infection-prevention-in-the-health-care-setting.

Sharafeldin, Noha, et al. “Outcomes of COVID-19 in Patients with Cancer: Report from the National COVID Cohort Collaborative (N3C) | Journal of Clinical Oncology.” Journal of Clinical Oncology, 2021, ascopubs.org/doi/10.1200/JCO.21.01074.

Tanoue, Lynn T., et al. “Lung Cancer Screening.” American Journal of Respiratory and Critical Care Medicine, vol. 191, no. 1, Jan. 2015, pp. 19–33, www.atsjournals.org/doi/full/10.1164/rccm.201410-1777CI, 10.1164/rccm.201410-1777ci.

Our World in Data. “Number of COVID-19 Patients in Hospital.” Our World in Data, 2020, ourworldindata.org/grapher/current-covid-patients-hospital.

Van Haren, Robert M., et al. “Impact of the COVID-19 Pandemic on Lung Cancer Screening Program and Subsequent Lung Cancer.” Journal of the American College of Surgeons, vol. 232, no. 4, Apr. 2021, pp. 600–605, www.sciencedirect.com/science/article/pii/S1072751520325254, 10.1016/j.jamcollsurg.2020.12.002.

Windsor, Matt. “How Does COVID-19 Affect Patients with Cancer? Largest U.S. Study Shares First Results - News.” UAB News, News, 9 June 2021, www.uab.edu/news/research/item/12100-how-does-covid-19-affect-patients-with-cancer-largest-u-s-study-shares-first-results.

Wu, Mingxin, et al. “Is COVID-19 a High Risk Factor for Lung Cancer?” Medicine, vol. 100, no. 1, 8 Jan. 2021, p. e23877, journals.lww.com/md-journal/fulltext/2021/01080/is_covid_19_a_high_risk_factor_for_lung_cancer___a.24.aspx, 10.1097/md.0000000000023877.

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2023-01-12