Recent Diagnostic Techniques and Their Implications towards Acute Myeloid and Chronic Neutrophilic Leukemia
DOI:
https://doi.org/10.58445/rars.876Keywords:
Leukemia, acute meyeloid , neutrophilicAbstract
Leukemia is characterized by the uncontrolled proliferation of abnormal white blood cells within bone marrow, leading to immaturities within blood cells. In acute myeloid leukemia and chronic neutrophilic leukemia, genetic mutations induced by either foreign or natural processes lead to the development of leukemia. Although leukemia is a diagnosable disease, the diverse subtypes and a complex, multi-step diagnosis makes identifying expedient, accurate diagnosis methods a top priority. With specific methods being attributed as the only means of diagnosing leukemia, and the importance of proper subtype classification in patient prognosis, the lack of research regarding novel diagnostic approaches remains a concern due to the important role leukemia classification plays in the prognosis of the patient. Currently, three diagnosis methods can be regarded as prevalent to the modern diagnosis of leukemia: epigenetics, molecular genetics, and cytogenetics. Each of these current methods are capable of identifying specific subtypes of leukemia. Furthermore, developing more detailed diagnosis criteria will provide better prognostic stratification. This review will cover various diagnosis methods regarding acute myeloid leukemia and chronic neutrophilic leukemia. Further inquiry in the area of diagnostics could reveal novel patterns within the diagnosis of Leukemia, furthering the ability to treat patients more specifically which can increase the prognosis of the patient.
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