Genetic Basis of Human Language Acquisition
DOI:
https://doi.org/10.58445/rars.1363Keywords:
Language Acquisition, Genetics, Vocal LearningAbstract
Humans possess the unique ability to speak sophisticated languages through vocal learning. Studies have tried to understand the biological basis of human language acquisition. In this review, we discuss research focusing on a family with an inherited language disorder that leads to the discovery of a gene encoding a transcription factor known as forkhead box P2 (FoxP2). Studies on other model organisms, such as birds and mice, have provided insights into the unique role of FoxP2 in language acquisition and how the mutation in FoxP2 affects its function. Finally, we propose future directions to deepen our understanding of the mechanism of FoxP2 action, the pathogenesis of FoxP2 mutation-associated language disorder and potential treatments.
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